<b>2014</b>—<b>2021</b>年浙江省余姚市居民胰腺癌死亡及寿命损失分析

徐苏英; 周振宇

doi:10.19428/j.cnki.sjpm.2023.22706

2014—2021年浙江省余姚市居民胰腺癌死亡及寿命损失分析

Death and life loss of pancreatic cancer among residents in Yuyao from 2014 to 2021

摘要

摘要:
目的了解浙江省余姚市居民胰腺癌死亡水平、变化趋势和寿命损失情况，为胰腺癌防控工作提供科学借鉴。
方法收集2014—2021年余姚市户籍居民死亡监测数据，计算胰腺癌粗死亡率（CMR）、标化死亡率（SMR）、潜在减寿年数（PYLL）、平均减寿年数（AYLL）、PYLL率（PYLLR）和平均年度变化百分比（AAPC）等指标。
结果 2014—2021年余姚市胰腺癌死亡860例，占同期全部恶性肿瘤死亡人数的6.25%，年均死亡率为12.86/10万，中国标准人口（简称“中标”）死亡率为7.08/10万，世界标准人口（简称“世标”）死亡率为5.17/10万，8年间粗死亡率呈上升趋势（t=-5.076，P=0.002）；男性胰腺癌死亡493例，年均死亡率14.95/10万，中标死亡率8.13/10万，世标死亡率6.24/10万；女性胰腺癌死亡367例，年均死亡率10.82/10万，中标死亡率6.02/10万，世标死亡率4.14/10万，男性死亡率高于女性（ $χ_{}^{2}$ =22.191，P<0.001）；胰腺癌最小死亡年龄27.52岁，最大94.52岁，死亡年龄中位数及四分位数［M（Q₁，Q₂）］为［71.13（63.21，78.87）］岁，男性死亡年龄［M（Q₁，Q₂）］为［69.61（62.30，77.06）］岁小于女性［72.48（64.63，81.09）］岁（t=-3.820，P<0.001）；胰腺癌死亡率随年龄增长呈现上升趋势（ $χ_{趋势}^{2}$ =1 110.844，P<0.001），75~岁死亡率达峰值（75.58/10万）后有所回落；8年间胰腺癌死亡所致PYLL为9 775.00人年，AYLL为14.33人年，PYLLR为1.53‰。
结论胰腺癌是导致余姚市居民死亡的重要死因，对寿命造成巨大损失。应以中老年人为重点人群，制定有针对性的防控策略，以减少胰腺癌的发病与死亡。

Abstract:
Objective To determine the death level， change trend and life loss of pancreatic cancer among residents in Yuyao， and to provide scientific reference for the prevention and control of pancreatic cancer.
Methods The death monitoring data of registered residents in Yuyao from 2014 to 2021 were collected to calculate crude mortality rate（CMR）， standardized mortality rate （SMR）， potential years of life lost （PYLL）， average years of life lost （AYLL）， PYLL rate （PYLLR）， average annual percent change （AAPC） and other indicators.
Results From 2014 to 2021， 860 cases of pancreatic cancer died in Yuyao， accounting for 6.25% of all malignant tumor deaths in the same period. The average annual mortality rate was 12.86/100 000， the age-standardized rate by Chinese standard population （ASRC） was 7.08/100 000， and the age-standardized rate by world Segi’s population （ASRW） was 5.17/100 1000. The CMR showed an upward trend in eight years （t=-5.076， P=0.002）. 493 men died of pancreatic cancer with an average annual mortality of 14.95/100 000， ASRC of 8.13/100 000， and ASRW was of 6.24/100 000. 367 women died of pancreatic cancer with an average annual mortality rate of 10.82/100 000， ASRC of 6.02/100 000， and ASRW of 4.14/100 000. The mortality rate of men was higher than that of women （χ²=22.191， P<0.001）. The minimum death age of pancreatic cancer is 27.52 years old， the maximum death age is 94.52 years old， and median age （Q₁， Q₂） of death was ［71.13（63.21， 78.87）］ years old. The death age of men ［69.61（62.30， 77.06）］ was less than that of women ［72.48（64.63， 81.09）］（t=-3.820， P<0.001）. The mortality rate of pancreatic cancer showed an upward trend with age （χ²_trend=1 110.844， P<0.001）， and the 75 year old mortality rate （75.58/100 000） fell after reaching the peak. PYLL caused by death of pancreatic cancer in 8 years was 9 775.00 person years， AYLL was 14.33 person years， and PYLLR was1.53‰.
Conclusion Pancreatic cancer is an important cause of death for residents in Yuyao， which has a huge loss of life. It is necessary to formulate targeted prevention and control strategies， with the middle-aged and elderly as the key population， to reduce the incidence and death of pancreatic cancer.

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