刘芳, 王教明, 李言, 徐琳, 刘蒲. 高血压和腹型肥胖与糖尿病患病的交互作用[J]. 上海预防医学, 2023, 35(9): 885-888. DOI: 10.19428/j.cnki.sjpm.2023.22889
引用本文: 刘芳, 王教明, 李言, 徐琳, 刘蒲. 高血压和腹型肥胖与糖尿病患病的交互作用[J]. 上海预防医学, 2023, 35(9): 885-888. DOI: 10.19428/j.cnki.sjpm.2023.22889
shu
LIU Fang, WANG Jiaoming, LI Yan, XU Lin, LIU Pu. Influence of interaction between hypertension and abdominal obesity on the prevalence of diabetes[J]. Shanghai Journal of Preventive Medicine, 2023, 35(9): 885-888. DOI: 10.19428/j.cnki.sjpm.2023.22889
Citation: LIU Fang, WANG Jiaoming, LI Yan, XU Lin, LIU Pu. Influence of interaction between hypertension and abdominal obesity on the prevalence of diabetes[J]. Shanghai Journal of Preventive Medicine, 2023, 35(9): 885-888. DOI: 10.19428/j.cnki.sjpm.2023.22889
shu

高血压和腹型肥胖与糖尿病患病的交互作用

Influence of interaction between hypertension and abdominal obesity on the prevalence of diabetes

    摘要
  • 摘要:
    目的 探讨高血压和腹型肥胖对糖尿病患病的交互作用，为糖尿病防治提供参考。
    方法 采用整群抽样的方法，以2019年上海市闵行区参加某社区老年人免费健康体检的人作为研究对象，收集指标包括健康体格检查和实验室生化指标测定的结果，最终11 914名体检对象被纳入本次研究。采用SPSS 16.0软件进行统计分析，利用相乘模型和相加模型评价糖尿病患病影响的交互作用。
    结果 腹型肥胖75.19%，高血压47.99%，高血压肥胖共患39.42%，糖尿病16.26%。将性别、年龄作为混杂因素纳入多因素logistic回归模型显示，腹型肥胖（OR=1.29，95%CI：1.14~1.46）、高血压（OR=2.93，95%CI：2.63~3.26）与糖尿病患病呈正相关。糖尿病患病的交互作用分析显示，高血压和腹型肥胖间不存在相乘交互效应（OR=0.98，95%CI：0.76~1.27），存在协同相加交互作用。交互作用超额相对危险度（RERI）=0.53（95%CI：0.09~0.98）、归因比（AP）=0.14（95%CI：0.02~0.26）、交互作用指数（SI）=1.24（95%CI：1.01~1.52），差异具有统计学意义（P<0.05）。
    结论 高血压和腹型肥胖对糖尿病患病存在协同相加作用，改善血压、控制体重可协同预防糖尿病的发生。

     

    Abstract:
    Objective To explore the effect of interaction of hypertension and abdominal obesity on morbidity of diabetes and to provide the scientific bases for preventing diabetes.
    Methods A total of 11 914 people who took the physical examination in 2019 were examined with cluster sampling method for the interaction analysis. The data was collected by physical measurements and laboratory tests. SPSS 16.0 and interaction models were used for data analysis.
    Results In the subjects there were 75.19% with abdominal obesity， 47.99% with hypertension， 16.26% with diabetes， and 39.42% had abdominal obesity plus hypertension. Multivariate logistic regression analysis showed， after adjusting gender and age， the abdominal obesity（OR=1.29， 95%CI：1.14‒1.46） and hypertension （OR=2.93， 95%CI： 2.63‒3.26） were related to high risk of diabetes. There was no multiplicative interaction effect between abdominal obesity and hypertension （OR=0.98，95%CI： 0.76‒1.27）. The additive interaction was significant between abdominal obesity and hypertension with RERI=0.53（95%CI：0.09‒0.98）， AP=0.14（95%CI：0.02‒0.26）， and SI=1.24（95%CI：1.01‒1.52）.
    Conclusion There is a synergistic effect on morbidity of diabetes between abdominal obesity and hypertension. The improvement of weight and control of blood pressure could prevent significantly the diabetes.

     

    • HTML全文
    • 参考文献(21)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回