Abstract: Objective To evaluate clinical effect of high-pressure injection and fallopian tube recanalization on patients with tubal infertility. Methods A group of 92 tubal infertile patients were divided into two groups of HSG and interventional treatment:Hysterosalpingography(HSG), high-pressure injection and fallopian tube recanalization were performed respectively. The pregnancy outcomes had been obtained six months to a year post-operatively. Results The difference of recanalization rates between the two groups of HSG and Interventional Treatment was remarkable (P<0.01). There were also statistical differences in the recanalization rates of proximate fallopian tube and the other part between HSG and Interventional Treatment (P<0.01). There were no significantly statistical differences between proximate fallopian tube and the other part of the two groups(P>0.05). The pregnancy outcome of proximate fallopian tube was higher than those of the other part after fallopian tube recanalization(P<0.01). Conclusion Application of high-pressure injection and fallopian tube recanalization can increase the clinical treatment effect on tubal infertile patient, reduce the trauma and decrease the costs of treatment at the same time.