抗疲劳中药对小鼠抗疲劳作用的实验研究

Anti-fatigue effect of herbs compound on mice: An experimental study

摘要: 目的观察抗疲劳中药复方对小鼠抗疲劳作用的影响。方法以不同剂量(1.35、0.90、0.45 g/kg)抗疲劳中药复方给小鼠连续灌胃30 d,测定小鼠负重游泳时间,并检测小鼠肝糖原含量及运动疲劳小鼠血清尿素氮的含量。结果与对照组比较,抗疲劳中药复方能显著延长小鼠负重游泳时间,增加小鼠肝糖原含量,减少小鼠运动后血清尿素氮含量,且差异具有统计学意义(P<0.05)。结论抗疲劳中药复方对小鼠有明显的抗疲劳作用。

Abstract: Objective To observe the anti-fatigue effects of herbs compound in mice. Methods Different doses(1.35, 0.90, 0.45 g/kg) of herbs compound were given to mice for 30 days. In the study, the time of loaded-swimming, levels of glycogen in liver and serum urea nitrogen (BUN) were detected in the animals. Results The time of swimming was significantly longer, the level of glycogen in liver higher but levels of serum BUN remarkably lower in the herbs compound group than those in the control (P<0.05). Conclusion The herbs compound has anti-fatigue effects on mice.