Abstract: Objective To estimate the prevalence of eight chronic non-communicable diseases (NCDs) and associated common risk factors among Chinese middle-aged and older population.Methods The prevalence of eight NCDs and five common risk factors for NCDs among adults aged 50 years and older were estimated based on the survey data from SAGE-China wave Ⅰ. Ordinal logistic regression models were performed to examine the associated risk factors and social determinates for multiple chronic conditions.Results Adjusting for design weights and post-stratification, the proportions of insufficient vegetables and fruits intake, low level of physical activity, current daily smoking use, obesity and frequent heavy drinker were 35.6%, 28.1%, 26.7%, 12.8% and 6.3%, respectively. And the prevalence of hypertension, arthritis, angina, chronic lung disease, diabetes, stroke, asthma and depression were 61.3%, 22.0%, 7.9%, 7.9%, 6.6%, 3.1%, 1.9% and 0.3%, separately. The proportion of multiple chronic conditions was 28.4%. The older elderly, women, living in the urban, more risk factors would increase the risk of multiple chronic conditions.Conclusion The prevalence of NCDs is very high and multiple chronic conditions are common among middle-aged and older population. Hence, more attentions should be paid and multiple effective control measures should be taken.