Abstract: Objective To investigate the environmental pollution status and infectious diseases in kindergartens and nurseries in 2012 in Baoshan District. MethodsThe questionaire was used in combination with data from monitoring of the disinfection effect of environment, monitoring analysis of routine infectious disease and others. Results The overall pass rate was 97.91% for environmental disinfection in kindergartens and nurseries, and it was higher in public kindergartens and nurseries than in private ones. The conventional infectious disease in kindergartens and nurseries was mainly hane-foot-and-mouth disease (HFMD), whose incidence was higher in private kindergartens and nurseries than in public ones. And in terms of regional distribution, the incidence of HFMD was higher in streets and towns with more infloating population than those with less. And the pass rate for the disinfection effect on the kindergartens nurseries and the incidence rate of HFMD were negatively correlated. Conclusion Kindergartens and nurseries in our district should strengthen the complete configuration of hardware and software, establish standardized system of disinfection and isolation, and develop daily disinfection system, so as to reduce infectious disease.