Abstract: Objective To analyze the epidemiologic characteristics of bacillary dysentery in Minhang District, Shanghai during 2005 and 2009, and to provide scientific basis for prevention and treatment of bacillary dysentery.Methods Data on bacillary dysentery epidemics were collected and analyzed by descriptive epidemiological study. And 55 strains of Shigella dysenteriae isolated in 2007-2009 were serotyped.Results Average incidence rate of bacillary dysentery reported was 19.06 per 100,000 in Minhang District of Shanghai from 2005 to 2009,ranging from 5.43 per 100,000 to 39.01 per 100,000,presenting a decreasing trend with each year.Incidence was the highest in infants and young children under four years old (189.38 per 100,000),and the top three numbers of patients were preschool children scattered at home,school children and workers. Bacterial serotyping showed that 36 of 55 strains were Shigella flexneri(65.45%) and 19 Shigella sonnei(34.55%),and the dominant Shigella flexneri were flexneri 2a,flexneri 4c,and flexneri 1a.Most of strains of the Shigella were susceptble to AMC,CFT,CTX,CIP and GEN.Conclusion The incidence rate of bacillary dysentery decreased in Minhang District. Controlling measures should be strengthened on infants and young children under four years old,preschool children scattered at home,school children and workers. AMC,CFT,CTX,CIP and GEN may be good alternatives for the treatment of diarrhea caused by Shigella in Shanghai Minhang area.