Abstract: Objective To investigate the sanitation status of dental model in medical institutions in Changning District of Shanghai, and to provide evidence for strengthening the disinfection management.Methods 40 medical institutions in Changning District of Shanghai were investigated by field sampling and detection.Results 92.5% of the investigated medical institutions disinfected dental models. In 168 dental model samples, the qualification rate of sanitary quality was 88.1%, while exceeded number of bacteria was the major reason for the unqualified. Among all dental model disinfection methods including ultraviolet irradiation, disinfectant soaking, disinfectant spraying and ozone, ultraviolet irradiation was the most widely used and disinfectant soaking was with the best effect. The storage sites of disinfected dental models including filling room, pollution area of sterilization room and other locations. Dental models stored in the filling room were with the highest qualification rate.Conclusion The current dental model sanitation status in medical institutions in Changning District of Shanghai is relatively unsatisfactory; supervision and inspection administration need to be strengthened by health and family planning administrative departments.