Abstract: Objective To provide scientific evidence for making strategies and measures for disease prevention and control, we analyzed the epidemiological characteristics and risk factors of hospitalized cases of severe acute respiratory infeetion(SARI) in a hospital of Huzhou City.Methods We ana-lyzed the data on SARI cases collected from the First People's Hospital of Huzhou between 2009 and 2010.Results The First People's Hospital of Huzhou reported 232 SARI cases,which accounted for 2.46% of all cases admitted to hospital in the same period.The crest-time was winter and spring,and the peak age was 0~5 years old children.Most of the clinical symptoms in the cases were fever,cough,angina,shortness of breath and so on,and 84.91% SARI cases were accompanied by pneumonia.With the binary logistic regression analysis,we established a regression model about the risk factors on the cases.Finally,body mass index,a history of cardiovascular disease and shortness of breath entered the regression model.They were the risk factors of the SARI cases.Conclusion SARI cases occur mainly in children in Huzhou,the crest-time being winter and spring,and most of the cases are accompanied by lower respiratory infection.The risk factors are body mass index,a history of cardiovascular disease, and so on.