Abstract: Objective To analyze the incidence of pneumoconiosis from 1956 to 2011 in Zhabei district in Shanghaiand to provide a basis for exploring intervention methods of pneumoconiosis.Methods The pneumoconiosis cases diagnosed in 1956-2011 were analyzed in Zhabei District.Results Since 1956,418 cases of pneumoconiosis have been diagnosed that mainly were stage Ⅰ, and tuberculosis rate was 13.40%. Male was dominant(92.58%), whose average age was 52.26 years with professional seniority being 21.05 years. Silicosis was dominant(60.00%), followed by founder pneumoconiosis(25.84%). Starting as a different era of dust exposure, the pneumoconiosis type became different significantly.The main types were silicosis and founder pneumoconiosis before the 1980s while the main types became welders pneumoconiosis and silicosis after the 1980s. After 2000, more welders pneumoconiosis were diagnosed that were even more than silicosis standing first on the list . The age of onset and professional seniority of pneumoconiosis were different significantly in different times. Different types of pneumoconiosis occurred at different ages of onset with different professional seniority.Conclusion The protection for dust-exposed work should be strengthened and the protection awareness of the workers should be improved so as to reduce the incidence of pneumoconiosis.