Abstract: Objective To study the value of colposcopy for the diagnosis of condyloma acuminatum. Methods To examine 128 cases of vulvar condyloma with colposcopy and make comparisons with the results of histopathologic tests. Results There were 67 cases of condyloma lesions found in cervix in histopathologic tests.In detection of condyloma acuminattum with colposcopy, the sensitivity was 92.5%, specificity 88.5%, false negative rate 7.5%, false positive rate 11.5%, accuracy rate 90.6%, positive predictive value 89.9%, negative predictive value 91.5%, Youden index was 0.8. Conclusion Colposcopy for diagnosis of condyloma is a new morphologic technique, convenient, practical, scatheless and highly effective.Cervical condyloma acuminatum can be early detected with colposcopy, which is important for prevention of cervical cancer and precancerous lesions.