Abstract: Objective To investigate the situation of group A rotavirus infection in this region, providing epidemiological data for clinical medicine. Methods The colloid gold fast method was used to detect the stool samples of 1 040 infants with acute diarrhea. Results Among the 1 040 samples, 183(17.6%) strains were detected positive for rotavirus, and the higher positive rate was found between 6 months and 2 years old infants (23.6%). The season peak was from November to January. Conclusion Rotavirus infection proves to be one of the leading causes of infantile diarrhea. It is suggested that in rotavirus epidemic period, infants aged 2 months to 2 years should be given vaccinations.