Abstract: Objective To ascertain the air quality as well as its affect factors in the patient waiting room and infusion room in municipal general hospitals in Huangpu District.Methods Detecting the hygiene indexes stipulated by "Specifications for Health Monitoring Technology in Public Places" and evaluating them according to "Hygiene Standards for Waiting Room" and " Hygiene Specifications of Central Ventilation and Air Conditioning Systems in Public Places".Results The passing rate for noise was 0.00% while that for carbon dioxide 24.07% in accordance with indoor hygiene indexes. The passing rate for PM₁₀ was 52.78% while that for the total number of bacteria 83.33% in accordance with the central ventilation and air conditioning systems hygiene indexes. The concentrations of carbon dioxide in the spaces were in positive linear correlation with the person densities, there were significant differences(P<0.01) between areas with different ventilation conditions in the same person density.Conclusion In the patients'waiting room and infusion room of the general hospitals,noises and high concentrations of car- bon dioxide are the worst problems in relation to air quality and affect factors. The concentrations of carbon dioxide are closely related to the ventilation condition and person density. The management of central ventilation and air conditioning systems needs to be standardized in general hospitals.